An independent provider of cardiovascular health care

In association with Phoenix Hospital Group

Research

Research underpins much of what is known about cardiovascular medicine and is the basis for clinical treatment guidelines.

The clinical evidence base comes from many sources including:

Observational studies and registries which observe what happens to patients receiving routine care.Trials of specific treatments which are compared with other treatments or placebo.

The strongest levels of evidence are usually considered to come from large randomised controlled trials (RCTs) usually aiming to establish whether or not a new treatment is better than the existing treatment. In these trials large groups of patients are randomly allocated to one or other treatments and the outcomes carefully evaluated, to discover which of the treatments is superior for patient outcomes.

All research should conform to the internationally accepted principles of Good Clinical Practice (GCP). Three of the fundamental principles are as follows:

Clinical trials should be conducted in accordance with the ethical principles that have their origin in the Declaration of Helsinki, and that are consistent with GCP and the applicable regulatory requirement(s).

Before a trial is initiated, foreseeable risks and inconveniences should be weighed against the anticipated benefit for the individual trial subject and society. A trial should be initiated and continued only if the anticipated benefits justify the risks.

The rights, safety, and well-being of the trial subjects are the most important considerations and should prevail over interests of science and society.

Doctors working in the Cardiovascular Health Clinic are involved in clinical research and you may be offered the opportunity to participate in research. This however is entirely at the patients discretion and patients are never under any obligation to engage in research.

There are many commercial and non-commercial organisations engaged in funding and undertaking clinical research.

The National Institute for Health Research (NIHR) supports research in the NHS through a Clinical Research Network (CRN) designed to treat the needs of patients and the public.

Click the links in the Consultant profiles to see Publications and Research Grants for Doctors working at The Cardiovascular Health Clinic: